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Carisoprodol Tablets Effective in Patients With Acute Lower Back Spasm

Carisoprodol 250 mg tablets taken 4 times daily appear to improve functional status and are well tolerated in patients with acute, muscle spasm of the lower back, according to research presented here at the American Academy of Pain Medicine (AAPM) 25th Annual Meeting.

Carisoprodol is a centrally acting skeletal-muscle relaxant indicated for the relief of discomfort associated with acute, painful musculoskeletal conditions in adults.

Lee Ralph, MD, San Diego Sports Medicine and Family Health Center and University of California San Diego School of Medicine, San Diego, California, presented the findings here at a poster session on January 30.

European Medicines Agency and Carisoprodol-containing Medicinal Products

The European Medicines Agency (EMEA) has recommended the suspension of marketing authorisations for all medicinal products containing carisoprodol. Carisoprodol products are available in 12 Member States under prescription, mainly for the treatment of acute lower back pain.

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Finalising its review, the Agency’s Committee for Medicinal Products for Human Use (CHMP) concluded that the risks of these medicines are greater than their benefits, and recommended the suspension of marketing authorisations in those Member States where the product is approved.